<p>Wood waste from construction and demolition (C&amp;D), harvesting, and wood manufacturing can be used to produce value-added bio-products such as engineered wood panels which reduces landfill use, avoids open burning, and displaces carbon-intensive materials. In this paper, cradle-to-grave Attributional Life Cycle Assessment is used to evaluate three wood waste sources (C&amp;D waste, small-diameter non-merchantable trees, and sawmill residues) for production of wood panels (Scenario 1) and compare the emissions to landfilling and incineration of the same amount of wood (Scenario 2), using the SimaPro software and the TRACI tool. Results show that producing 1 tonne of wood panels generates 506&#xa0;kg CO₂ eq., representing a 66% reduction relative to the emissions that would have occurred if the same quantity of wood were instead landfilled (for C&amp;D wood waste) and incinerated (for small-diameter non-merchantable trees and sawmill residues). Manufacturing processes dominate environmental impacts, accounting for 48% of global warming potential, and more than 80% of acidification, eutrophication, and smog formation impacts. Sensitivity analysis reveals that the transportation distance of wood waste sources to the&#xa0;manufacturing plant and the distribution of final products have the most significant effect. Increasing the transportation distance of wood waste sources by 50% caused a 45% rise in ozone depletion.</p> Graphical Abstract <p></p>