<p>It is well established that positive contact reduces prejudice and negative contact increases it. However, negative and positive contact may interact to affect prejudice, rather than merely having opposite effects. We investigated whether positive contact with people with schizophrenia predicted less social distance, whether fear mediated this relationship, and whether negative contact moderated (i.e., facilitated) this mediated relationship. Participants (<i>N</i> = 393) reported their frequency of positive and negative contact, fear, and social distance from people with schizophrenia. The facilitation hypothesis was partially supported. Positive contact predicted (less) social distance and this relationship was mediated by fear. Negative contact moderated (facilitated) the direct relationship between positive contact and social distance, but did not moderate the mediated relationship via fear. Going beyond asymmetries to interactions is important in understanding how to improve contact interactions with people with schizophrenia. Implications for contact and anti-schizophrenia prejudice are discussed.</p>