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<p>This study aimed to assess the effectiveness of ChatGPT, an AI-based language model, in aiding healthcare professionals with selecting suitable medications for the treating of leishmaniasis. A panel of medical experts and specialists in tropical diseases assessed the recommendations provided by ChatGPT for 10 hypothetical clinical scenarios related to leishmaniasis. The main objective was to determine the utility of ChatGPT in facilitating informed decision-making regarding drug choices for managing leishmaniasis. ChatGPT consistently provided valuable suggestions for potential drug repurposing in the treatment of leishmaniasis across all scenarios, aligning with current medical research. Despite the lack of specific treatment guidelines, ChatGPT’s suggestions proved beneficial, presenting potential avenues for medication repurposing. These findings suggest that ChatGPT shows promise as a useful tool for drug repurposing in leishmaniasis therapy, assisting in the identification of potential pharmaceutical options. However, it is important to acknowledge certain limitations, such as the requirement for additional clinical data and the inability to adjust therapy.</p>

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AI-powered medicine repurposed to identify new leishmaniasis treatments

  • 期刊论文

  • 发表日期：

    2025年7月31日

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  • Hinpetch Daungsupawong,
  • Viroj Wiwanitkit

摘要

This study aimed to assess the effectiveness of ChatGPT, an AI-based language model, in aiding healthcare professionals with selecting suitable medications for the treating of leishmaniasis. A panel of medical experts and specialists in tropical diseases assessed the recommendations provided by ChatGPT for 10 hypothetical clinical scenarios related to leishmaniasis. The main objective was to determine the utility of ChatGPT in facilitating informed decision-making regarding drug choices for managing leishmaniasis. ChatGPT consistently provided valuable suggestions for potential drug repurposing in the treatment of leishmaniasis across all scenarios, aligning with current medical research. Despite the lack of specific treatment guidelines, ChatGPT’s suggestions proved beneficial, presenting potential avenues for medication repurposing. These findings suggest that ChatGPT shows promise as a useful tool for drug repurposing in leishmaniasis therapy, assisting in the identification of potential pharmaceutical options. However, it is important to acknowledge certain limitations, such as the requirement for additional clinical data and the inability to adjust therapy.