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Purpose of the review <p>Breast cancer in young adult (YA) women aged 18–39 years old presents distinct challenges. This review synthesizes current evidence on treatment strategies while emphasizing multidisciplinary collaboration.&#xa0;</p> Recent findings <p>Rising incidence, particularly among Hispanic and Asian-American populations, coupled with aggressive tumor biology and advanced-stage diagnoses contributes to poorer survival outcomes than for those diagnosed at ages ≥40 years old. Diagnostic delays stem from limited screening and dense breast tissue. Treatment decisions, including surgical and systemic therapies, are influenced not only by tumor biology but also by genetic risk, fertility concerns, and psychosocial factors. Advances in targeted therapies and radiation techniques offer promising outcomes but require individualized planning to mitigate long-term toxicity.&#xa0;</p> Summary <p>Despite advancements in the treatment of breast cancer, age-specific guidelines and ongoing research are imperative for improving outcomes and quality of life for YA patients with breast cancer.</p>

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Navigating Breast Cancer in Young Adults: Diagnostic and Therapeutic Considerations

  • 期刊论文

  • 发表日期：

    2025年11月21日

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  • Andrea N. Riner,
  • Patrick W. Harbour,
  • Therese Y. Andraos,
  • Doreen M. Agnese,
  • Nerea M. Lopetegui,
  • Natasha Monga,
  • Sara Myers

摘要

Purpose of the review

Breast cancer in young adult (YA) women aged 18–39 years old presents distinct challenges. This review synthesizes current evidence on treatment strategies while emphasizing multidisciplinary collaboration. 

Recent findings

Rising incidence, particularly among Hispanic and Asian-American populations, coupled with aggressive tumor biology and advanced-stage diagnoses contributes to poorer survival outcomes than for those diagnosed at ages ≥40 years old. Diagnostic delays stem from limited screening and dense breast tissue. Treatment decisions, including surgical and systemic therapies, are influenced not only by tumor biology but also by genetic risk, fertility concerns, and psychosocial factors. Advances in targeted therapies and radiation techniques offer promising outcomes but require individualized planning to mitigate long-term toxicity. 

Summary

Despite advancements in the treatment of breast cancer, age-specific guidelines and ongoing research are imperative for improving outcomes and quality of life for YA patients with breast cancer.