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Purpose of Review <p>This review discusses the advancements made in diagnosis, management, and treatment of breast cancer-related lymphedema (BCRL), with a primary focus on the significant surgical interventions and reported outcomes.</p> Recent Findings <p>Variations in surgical interventions exist due to surgeon preference and skillset. Some preventive approaches include LYMPHA, S-LYMPHA, axillary reverse mapping, and TLAR with an incidence of BCRL of 4.3%, 3%, 4.1%, and 4% respectively after axillary lymph node dissection (ALND). Therapeutic approaches may include lymphovenous bypass surgery (LVB) as well as vascularized lymph node transfer (VLNT), which have shown significant reduction in arm circumference with improved patient satisfaction. LVB can also be performed at the time of ALND with a reduction in BCRL from 32% to 9.5%.</p> Summary <p>Overall, these advancements regarding BCRL have drastically evolved over two decades. Therapeutic surgical options are available; however, the emphasis on prevention of lymphedema remains a forefront in surgical approach to the axilla with promising results.</p>

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Advancements in Treatment and Surgery for Breast Cancer Related Lymphedema

  • 期刊论文

  • 发表日期：

    2025年6月13日

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  • Alicia Huff Arnold,
  • Christina H. Bae,
  • Shawn M. Doss,
  • Mohamed Nofal,
  • Shaan Haider,
  • Isha Darshane,
  • Cameron Jackson,
  • Sweta Munagapati,
  • Christopher Painter,
  • Kyra Urquhart-Foster,
  • Katharine Tracy,
  • Alexandra Metzger,
  • Lauren A. Herrera,
  • Hari Kashyap

摘要

Purpose of Review

This review discusses the advancements made in diagnosis, management, and treatment of breast cancer-related lymphedema (BCRL), with a primary focus on the significant surgical interventions and reported outcomes.

Recent Findings

Variations in surgical interventions exist due to surgeon preference and skillset. Some preventive approaches include LYMPHA, S-LYMPHA, axillary reverse mapping, and TLAR with an incidence of BCRL of 4.3%, 3%, 4.1%, and 4% respectively after axillary lymph node dissection (ALND). Therapeutic approaches may include lymphovenous bypass surgery (LVB) as well as vascularized lymph node transfer (VLNT), which have shown significant reduction in arm circumference with improved patient satisfaction. LVB can also be performed at the time of ALND with a reduction in BCRL from 32% to 9.5%.

Summary

Overall, these advancements regarding BCRL have drastically evolved over two decades. Therapeutic surgical options are available; however, the emphasis on prevention of lymphedema remains a forefront in surgical approach to the axilla with promising results.