Changes in Radiation Therapy: New Ultrahypofractionated Radiation, Repeat Breast Conservation Therapy in the Management of Breast Recurrence with Re-irradiation, Proton Therapy

Management of breast cancer is multidisciplinary, balancing local and systemic control between treatment modalities. Surgical, radiation, and medical therapies are combined to give the best prognosis. The goal of this review is to examine the advancements in radiotherapy in the treatment of breast cancer.

Published data supports the shortening of radiation schedules through ultrahypofractionation and utilizing new energy sources through proton beam radiation. Emerging techniques have minimized radiation dosage to organs at risk and skin when compared to traditional radiation sources and plans. Traditionally an ipsilateral breast tumor recurrence after breast conservation therapy necessitated mastectomy. Re-irradiation is now an alternative option with comparable outcomes.

Advances in radiotherapy have contributed to more patients choosing breast-conserving surgery over mastectomy. This has prompted the investigation of alternative technologies and techniques to decrease toxicities, while maintaining oncologic efficacy