<p>The control of phytophagous mites and other invertebrate pests in agricultural systems has long relied heavily on chemical pesticides. The extensive and indiscriminate use of synthetic pesticides in crop protection poses significant risks to predatory mites, which are vital biological control agents in Integrated Pest Management (IPM) programmes. In this review, we summarize the current literature on the toxicity of pesticides to predatory mites, categorizing the effects as lethal and sublethal. Direct exposure to pesticides can cause lethal effects, leading to high mortality rates, whereas sublethal exposure may impair key biological traits such as fecundity, longevity, predation rate and developmental success. Moreover, non-target effects differ among chemical classes, and developmental stages of predatory mites, highlighting the complexity of pesticide-mite interactions. Understanding these effects is crucial for designing IPM strategies that minimize negative impacts on predatory mites while sustaining their ecological services. This review highlights the diverse effects of pesticides on predatory mites and stresses the importance of incorporating chemical selectivity and conservation of natural enemies into sustainable crop protection programmes.</p>