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Numerical analysis of silicon nitride and perovskite nanomaterial assisted SPR biosensor for dengue cell detection

  • Nikhil Pratap Singh,
  • Adarsh Chandra Mishra,
  • Sapana Yadav,
  • Pooja Lohia,
  • D. K. Dwivedi,
  • Ammar M. Tighezza,
  • M. Khalid Hossain

摘要

A surface plasmon resonance (SPR) sensor for the detection of the dengue virus has been presented with excellent sensitivity. The design consists of a heterojunction of copper metal, silicon nitride, barium titanate, and black phosphorus nanomaterials deposited over BK7 prism. Thickness of each layer is optimized to achieve the highest possible sensitivity. The proposed sensor has the ability to identify both normal and infected blood samples, which include components such as plasma, platelets, and hemoglobin. The sensor offers angular sensitivity for plasma, platelets, and hemoglobin cells of 146.53°/RIU, 226.89°/RIU, and 300°/RIU with their figure of merit values of 137.73, 183.78 and 264 RIU−1 respectively. Further, to validate the position of resonance angle and reflection phenomena, phase change and electric field enhancement factor is also investigated. The novelty of the design lies in proper selection of heterojunction based on Cu metal which provides high sensitivity for dengue cells.