The increasing adoption of 6U–8U CubeSat platforms for Earth observation, communication, and scientific missions has created a growing demand for compact, high-performance attitude control actuators capable of supporting agile mission profiles under strict volume and mass constraints. This paper presents a mission-driven, system-level design and sizing methodology for an in-house reaction wheel pyramid assembly fully constrained within a standard 1U (10 \(\times \) 10 \(\times \) 10 \(\hbox {cm}^{3}\) ) volume and scalable across 6U, 6U-XL, and 8U CubeSat platforms. The proposed methodology starts from time-constrained agile mission requirements representative of single-pass multi-strip imaging scenarios and systematically propagates these requirements to spacecraft inertia modeling, reaction wheel torque, and angular momentum sizing. A conservative worst-case approach based on a required slew rate of 5 deg/s yields angular momentum requirements ranging from 0.0113 to 0.0204 N \(\cdot \) m \(\cdot \) s across the considered platforms. A four-wheel pyramidal configuration with a cant angle of \(35.26^\circ \) is adopted to provide full three-axis control authority with single-wheel failure tolerance. To satisfy the derived momentum requirements within the 1U volume constraint, high-density tungsten flywheels are selected, enabling compact geometries with radii of 20 mm and thicknesses between 5.75 and 10.32 mm. Torque analysis results in minimum single-wheel torque demands between 6.14 and 11.03 mN \(\cdot \) m, while a motor trade study demonstrates continuous torque margins exceeding \(2\times \) in the worst-case 8U scenario using commercially available brushless DC motors. CAD-based geometric verification confirms the feasibility of integrating the complete four-wheel assembly within a centralized 1U volume, with an estimated total mass of approximately 1.96 kg, corresponding to about 14% of an 8U spacecraft. The presented architecture demonstrates the feasibility of integrating a compact fault-tolerant four-wheel reaction wheel pyramid within a centralized 1U volume while maintaining scalability across 6U–8U CubeSat platforms. The proposed design establishes a practical and scalable foundation for compact, fault-tolerant attitude control architectures suitable for agile CubeSat missions and future flight-qualified ADCS implementations.