This paper uses a generic high lift reentry vehicle geometry to get unsteady RANS results for aerothermal heating on the out- and inside of the body using the DLR TAU code coupled with a structural solver. The DLR CoNF \(^\text {2}\) aS \(^\text {2}\) tool chain (Coupled Numerical Fluid Flight Mechanic And Structure Simulation) is used to perform a coupled Fluid/Structure/Flight-mechanic simulation along a generic flight trajectory. From these high-fidelity results, in a second step, an aerothermal database along the trajectory is produced, containing the heat flux and temperature distribution on the surface. Replacing the flow solver with a much faster database response, the same flight mechanic coupled structural heating simulation is performed and compared with the former method. Afterwards, a modified off-design trajectory is calculated and the heating gets interpolated from the database heat flux along the new trajectory and compared with the initial computed flight path to analyze the sensitivity of the database method at offset flight conditions. Since the database method is by orders of magnitude faster, this will accelerate the design process of future vehicle geometries regarding TPS and trajectory development.