Improved dosimetric detection of ionizing radiation with gold-coated fiber optics
摘要
More than half of cancer patients undergoes radiation therapy regimen. Indeed, the accuracy of the delivered radiation dose in the planning target volume (PTV) is depending on the sensitivity and accuracy of the used dosimetric tools. In vivo dose measurements, improved dosimeter can help identify systematic and random errors in the delivery of treatment and, therefore, play an important role in quality assurance. Recently, the photon response of fiber optics has been investigated by many research groups. Dosimeter produced from fiber optics increases its spatial resolution making absorbed dose reporting accurate. The study aims to verify the dosimetric use of fiber optics in interface dosimetry and to investigate a novel enhanced dose technique using different gold thicknesses as a coating for fiber optics.
MethodThe commercially available Ge-doped silicon dioxide (SiO2) manufactured by (Cor Active, Canada) with a core diameter of 50.9 ± 4.1 μm were irradiated using a 250 kVp superficial X-ray machine and a dose of 3 Gy. Before irradiation, the fiber optics were prepared in few steps; firstly, it was preheated, annealed and then its reading were performed. The fiber optics pieces were coated with gold in different thicknesses; after that, they were prepared and exposed to the same radiation dose to explore the effect of different gold coating thicknesses on the dosimetric behavior of the fiber optics.
ResultsThe results show an enhanced dosimetric behavior of the fiber optics when increasing its coated gold (Au) layer thickness; the highest percentage dose enhancement of approximately 160% was obtained at the gold coated thickness 80 nm. While a slight relatively enhanced dosimetry was obtained at the first thickness of coating gold (20 nm). These results pave the way to develop the fiber optics dosimeters, specifically used in radiotherapy.
ConclusionThe small pieces of gold coated fiber optics could be useful to place inside the patient body to monitor the dose delivered in different place as PTV and organ at risk (OAR), moreover, the fiber optics dosimeter is applicable to wide use in radiotherapy due to its flexibility, durability and economically reused few times.