Feasibility of patient weight-based size-specific dose estimates for pediatric CT: a comparison with water-equivalent diameter
摘要
As weight-based size-specific dose estimates (SSDE) have not been extensively studied in pediatric CT, this study aimed to evaluate the feasibility of using patient body weight as an alternative to water-equivalent diameter (Dw) for calculating SSDE in pediatric chest and abdominal computed tomography (CT).
MethodsRetrospective data were collected from 256 pediatric patients (age < 18 years) who underwent CT chest (n = 104) and CT abdomen (n = 152) examinations. For each scan, a region of interest (ROI) was contoured at the central slice (mid-scan range) to determine the mean CT number and area, which were used to calculate the water-equivalent diameter (Dw). The weight-based Dw (Dwweight) was estimated using linear regression derived from the correlation between patient body weight and Dw. SSDE based on Dw (SSDEDw) was calculated according to the American Association of Physicists in Medicine Report No. 220, while SSDE based on body weight (SSDEweight) was determined using a conversion formula corresponding to Dwweight. Pearson correlation coefficients (r) and Bland–Altman analysis were used to assess the agreement between the two calculation methods.
ResultsThe mean patient body weight of 34.14 ± 20.58 kg (range: 2.5–90 kg) was obtained in this study. SSDEDw values were 3.99 ± 3.82 mGy (range: 0.57–27.79 mGy) for chest CT and 9.53 ± 5.58 mGy (range: 2.10–26.35 mGy) for abdominal CT. The corresponding SSDEweight values were 4.08 ± 4.36 mGy (range: 0.58–34.24 mGy) for chest CT and 9.54 ± 5.68 mGy (range: 3.13–31.96 mGy) for abdominal CT. A statistically significant correlation was found between SSDEweight and SSDEDw, with r = 0.98 for chest and r = 0.99 for abdomen (p < 0.01). Bland–Altman analysis demonstrated strong agreement between the two methods.
ConclusionsThis study shows that SSDE based on patient body weight is a reliable surrogate for estimating radiation dose in pediatric CT scans. It offers a simplified and faster method for CT dosimetry calculation in clinical settings.