Hadron therapy in radiation oncology and why BNCT is a paradigm shift

期刊论文
出版模式：

开放获取
发表日期：

2024年5月2日

查看全文

Wolfgang A. G. Sauerwein,
Kazuyo Igawa,
Joël Herault,
Piero Fossati,
Saverio Altieri,
Raymond L. Moss,
Andrea Wittig

摘要

Purpose

Hadrons, i.e. particles that are heavier than electrons, are playing an increasingly important role in radiation oncology. Due to the high investment costs for the necessary infrastructure, this option is only available in specialized centers.

Methods

This article describes some of the physical properties that make hadrons attractive for external beam radiation therapy (EBRT), but also some of the challenges that need to be considered.

Results

The importance of linear energy transfer for biological effects is discussed.

Conclusions

In addition to the use of charged particles, the importance of neutrons for radiotherapy is also highlighted, in particular the properties of boron neutron capture therapy (BNCT), which open up completely new possibilities for the further development of EBRT.