<p>In specialized engineering applications, such as bone implants subjected to loads in different directions and energy absorption, porous structures are required to exhibit comprehensive mechanical properties. This design approach offers valuable insights for enhancing the biocompatibility of bone implants and improving the protective performance of energy absorbers. A homogenized periodic boundary condition finite element simulation was employed to investigate the mechanical properties of hybrid lattice structures. The relationship between the elastic modulus, anisotropic characteristics, deformation, and damage mechanisms of different structures under various periodic boundary loads was analyzed, focusing on single lattice structures with complementary elastic moduli. The results indicated that within single lattice structures, plate lattice structures exhibit superior mechanical properties compared to shell or rod structures. Under conditions suitable for mechanical forming and bone implant relative density, hybrid lattice structures composed of a 25% volume fraction of rhombic dodecahedron lattice structure (RD) and a 15% volume fraction of optimized transverse rod structure (OTR), as well as those composed of a 30% volume fraction RD and a 10% volume fraction transverse rod lattice structure (TR), exhibited nearly isotropic mechanical properties. Within the spatial domain, the failure mode of the structure is influenced by the direction of external load, material distribution, and aperture positions. It indicates that by designing hybrid structures based on the complementary elastic moduli of different single lattice structures, more comprehensive and adjustable mechanical properties can be achieved. This approach leverages advantages that single lattice structures alone do not possess.</p>