<p>We investigate properties of boundary orbits (separatrices) of canonical regions (basins/neighbourhoods of equilibria) in holomorphic flows with real-valued time. We establish the continuity of transit times along these boundary orbits and classify possible path components of the boundary of flow-invariant domains. Thus, we provide central tools for topological and geometric constructions aimed at examining the role of blow-up scenarios in separatrix configurations of basins of simple equilibria and global elliptic sectors: First, we prove that the boundary of basins of centers is entirely composed of double-sided separatrices with a blow-up in finite positive <i>and</i> finite negative time. Second, we show that the separatrices of node and focus basins (sinks and sources) exhibit a finite-time blow-up in the same time direction in which the orbits within the basin tend towards the equilibrium. Additionally, we propose a counterexample to the claim in Theorem 4.3 (3) in [<i>The structure of sectors of zeros of entire flows</i>, K. Broughan (2003)], demonstrating that a blow-up does not <i>necessarily</i> have to occur in <i>both</i> time directions. Third, we describe the boundary structure of global elliptic sectors. It consists of the multiple equilibrium, one incoming and one outgoing separatrix attached to it, and at most countably many double-sided separatrices.</p>