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<p>A woman in her 70s was referred for evaluation of a small (8&#xa0;mm) hepatic nodule detected on magnetic resonance imaging (MRI). The lesion demonstrated high signal intensity on diffusion-weighted imaging (DWI) with low apparent diffusion coefficient (ADC) values, which is atypical for small hepatocellular carcinoma (HCC). Contrast-enhanced ultrasonography (CEUS) revealed washout within 60&#xa0;s, which is also atypically early for HCC. Histopathological examination confirmed hepatic mucosa-associated lymphoid tissue (MALT) lymphoma. The combination of high signal intensity on DWI, a low ADC value, and early washout on CEUS is particularly useful in identifying small atypical hepatic tumors, such as MALT lymphoma, that mimic HCC.</p>

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Combined diffusion-weighted MRI and contrast-enhanced ultrasonography in diagnosing small hepatic MALT lymphoma mimicking hepatocellular carcinoma

  • 期刊论文

  • 发表日期：

    2025年10月1日

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  • Sounosuke Yamato,
  • Takaaki Sugihara,
  • Takuya Kihara,
  • Emiko Kanemura,
  • Yoshiki Hoshino,
  • Takakazu Nagahara,
  • Yudai Ota,
  • Kyohei Okuda,
  • Satoshi Kuwamoto,
  • Hajime Isomoto

摘要

A woman in her 70s was referred for evaluation of a small (8 mm) hepatic nodule detected on magnetic resonance imaging (MRI). The lesion demonstrated high signal intensity on diffusion-weighted imaging (DWI) with low apparent diffusion coefficient (ADC) values, which is atypical for small hepatocellular carcinoma (HCC). Contrast-enhanced ultrasonography (CEUS) revealed washout within 60 s, which is also atypically early for HCC. Histopathological examination confirmed hepatic mucosa-associated lymphoid tissue (MALT) lymphoma. The combination of high signal intensity on DWI, a low ADC value, and early washout on CEUS is particularly useful in identifying small atypical hepatic tumors, such as MALT lymphoma, that mimic HCC.