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<p>This article presents the case of a&#xa0;young patient with pityriasis lichenoides chronica (PLC), a&#xa0;rare, chronic inflammatory dermatosis that predominantly occurs in childhood and adolescence. The etiopathogenesis is incompletely understood; preceding infections and T‑cell-mediated immune mechanisms are discussed as possible triggers. Clinically, PLC is characterized by disseminated, brownish–orange papules and thin, finely scaling plaques, typically located on the trunk and extremities. A&#xa0;characteristic feature is the so-called “coffin-lid phenomenon,” in which the intact scale detaches when the lesion is scratched. Histopathological findings show a&#xa0;parakeratosis, a&#xa0;moderately cellular interface dermatitis with few&#xa0;necrotic keratinocytes, but also spongiosis and lymphocytic exocytosis. No standardized treatment exists; topical corticosteroids, calcineurin inhibitors, ultraviolet‑B (UVB) phototherapy, macrolides and in severe cases methotrexate have proven effective. A&#xa0;pediatric case is presented to illustrate the typical relapsing course and the potential for spontaneous, complete resolution without residual changes.</p>

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Pityriasis lichenoides chronica – eine wichtige Differenzialdiagnose im Kindesalter

  • 期刊论文

  • 发表日期：

    2025年10月29日

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  • Laura Schneller,
  • Christine Wagger

摘要

This article presents the case of a young patient with pityriasis lichenoides chronica (PLC), a rare, chronic inflammatory dermatosis that predominantly occurs in childhood and adolescence. The etiopathogenesis is incompletely understood; preceding infections and T‑cell-mediated immune mechanisms are discussed as possible triggers. Clinically, PLC is characterized by disseminated, brownish–orange papules and thin, finely scaling plaques, typically located on the trunk and extremities. A characteristic feature is the so-called “coffin-lid phenomenon,” in which the intact scale detaches when the lesion is scratched. Histopathological findings show a parakeratosis, a moderately cellular interface dermatitis with few necrotic keratinocytes, but also spongiosis and lymphocytic exocytosis. No standardized treatment exists; topical corticosteroids, calcineurin inhibitors, ultraviolet‑B (UVB) phototherapy, macrolides and in severe cases methotrexate have proven effective. A pediatric case is presented to illustrate the typical relapsing course and the potential for spontaneous, complete resolution without residual changes.