Scholarlink

Introduction <p>The objective of this study was to determine the number of people within glycated haemoglobin (HbA1c) targets and achieving weight-loss goals during the first 5&#xa0;years after type 2 diabetes (T2D) diagnosis and to explore the relationship between early weight loss and glycaemic control in routine care in Spain.</p> Methods <p>This was an observational retrospective study using IQVIA’s electronic medical record database, including adults aged&#xa0;≤&#xa0;65&#xa0;years newly diagnosed with T2D. Variables included baseline sociodemographic/clinical characteristics, yearly HbA1c and weight data, and treatment patterns. Descriptive statistics and regression analyses were used.</p> Results <p>A total of 8973 people with T2D were included (mean age 53&#xa0;years; mean baseline HbA1c 7.7%; obesity at diagnosis: 64%). During the first 5&#xa0;years post-T2D diagnosis, 46–63% of the population did not have HbA1c&#xa0;&lt;&#xa0;6.5%, and&#xa0;&gt;&#xa0;60%, and&#xa0;&gt;&#xa0;80% of subjects did not achieve&#xa0;≥&#xa0;5% and&#xa0;≥&#xa0;10% weight loss, respectively. Early weight loss goal achievement (1st year after diagnosis) and weight loss magnitude were associated with a higher percentage of people with HbA1c&#xa0;&lt;&#xa0;6.5%.</p> Conclusions <p>Many individuals with T2D did not have HbA1c&#xa0;&lt;&#xa0;6.5% in the first 5&#xa0;years after diagnosis and did not achieve&#xa0;≥&#xa0;5% or&#xa0;≥&#xa0;10% weight loss. Early weight loss after T2D diagnosis was associated with higher likelihood of achieving early glycaemic control.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Glycaemic and Weight Control in People Aged 65 or Younger Newly Diagnosed with Type 2 Diabetes in Spain: Insights from the PRIORITY-T2D Study

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年5月19日

查看全文
  • Emilio Ortega,
  • Jennifer Redondo-Antón,
  • Silvia Díaz-Cerezo,
  • Miriam Rubio-de Santos,
  • Irene Romera

摘要

Introduction

The objective of this study was to determine the number of people within glycated haemoglobin (HbA1c) targets and achieving weight-loss goals during the first 5 years after type 2 diabetes (T2D) diagnosis and to explore the relationship between early weight loss and glycaemic control in routine care in Spain.

Methods

This was an observational retrospective study using IQVIA’s electronic medical record database, including adults aged ≤ 65 years newly diagnosed with T2D. Variables included baseline sociodemographic/clinical characteristics, yearly HbA1c and weight data, and treatment patterns. Descriptive statistics and regression analyses were used.

Results

A total of 8973 people with T2D were included (mean age 53 years; mean baseline HbA1c 7.7%; obesity at diagnosis: 64%). During the first 5 years post-T2D diagnosis, 46–63% of the population did not have HbA1c < 6.5%, and > 60%, and > 80% of subjects did not achieve ≥ 5% and ≥ 10% weight loss, respectively. Early weight loss goal achievement (1st year after diagnosis) and weight loss magnitude were associated with a higher percentage of people with HbA1c < 6.5%.

Conclusions

Many individuals with T2D did not have HbA1c < 6.5% in the first 5 years after diagnosis and did not achieve ≥ 5% or ≥ 10% weight loss. Early weight loss after T2D diagnosis was associated with higher likelihood of achieving early glycaemic control.