Risikoadaptierte Prävention bei Brust- und Eierstockkrebs

Riskadapted cancer prevention has moved to the centre of oncology through the National Decade Against Cancer. Hereditary breast and ovarian cancer have pioneered this field. By including genetic and non-genetic factors, personalised risk prediction has become possible for those affected, which forms the basis for risk-stratified screening and prevention. While in the past two decades the focus was on the about 30 % of affected women with a (high-)risk situation, the focus is now being directed towards the general population. The goal is a comprehensive personalised risk prediction for all, as a basis for the offer of risk-adapted preventive measures with a chance to improve outcome.