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<p>Chronic myeloid leukemia is a myeloproliferative neoplasm where isolated CNS blast crisis is very rare. A cns directed therapy is most appropriate in such cases along with craniospinal irradiation due to poor cns penetrations by TKIs. We report such a case of isolated cns B- lymphoid blast crisis in a known case of CML.</p>

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Isolated CNS B-Lymphoid Blast Crisis in Chronic Myeloid Leukemia: A Rare Presentation

  • 期刊论文

  • 发表日期：

    2026年6月29日

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  • Nikita Choudhary,
  • Surbhi Singh,
  • Rajul Bodkha,
  • Astha Srivastava,
  • Aastha Gupta,
  • Ritu Garg

摘要

Chronic myeloid leukemia is a myeloproliferative neoplasm where isolated CNS blast crisis is very rare. A cns directed therapy is most appropriate in such cases along with craniospinal irradiation due to poor cns penetrations by TKIs. We report such a case of isolated cns B- lymphoid blast crisis in a known case of CML.