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<p>36-year-old lady with Primary Sjogren’s Syndrome presented with progressive dyspnoea and dry cough since 6 months. On evaluation, there were multiple nodular cavitating lesions in lung on CT scan, which were hypermetabolic on FDG-PET. Biopsy was consistent with extra-nodal marginal zone B cell lymphoma of MALT. She was treated with Rituximab, Cyclophodphamide, Doxorubicin, Vincristine and Prednisolone based chemotherapy with good clinical and radiological response. Hence, lymphomas, including MALT lymphomas should be suspected when a Sjogren’s patient presents with multiple pulmonary nodules.</p>

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Mysterious Lung Nodules in a Case of Primary Sjogren Syndrome

  • 期刊论文

  • 发表日期：

    2025年4月26日

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  • Bodhibrata Banerjee,
  • Niladri Bhowmick,
  • Charanpreet Singh,
  • Suruthy Narayanasami,
  • Amanjit Bal,
  • Sanjay Jain,
  • Varun Dhir

摘要

36-year-old lady with Primary Sjogren’s Syndrome presented with progressive dyspnoea and dry cough since 6 months. On evaluation, there were multiple nodular cavitating lesions in lung on CT scan, which were hypermetabolic on FDG-PET. Biopsy was consistent with extra-nodal marginal zone B cell lymphoma of MALT. She was treated with Rituximab, Cyclophodphamide, Doxorubicin, Vincristine and Prednisolone based chemotherapy with good clinical and radiological response. Hence, lymphomas, including MALT lymphomas should be suspected when a Sjogren’s patient presents with multiple pulmonary nodules.