<p>Elevators, as an enclosed and often crowded space, pose a high risk of airborne infections due to ineffective ventilation. To mitigate this issue, this study introduces a reinforced exhaust at low velocity (RELV) system, specifically designed to enhance aerosol removal efficiency in elevators. The performance of the RELV system was assessed through computational fluid dynamics (CFD) simulations, employing the Renormalization Group (RNG) <i>k</i>–<i>ε</i> turbulence model to simulate airflow and the Lagrangian method to track particle motion. The RELV system was benchmarked against three conventional ventilation strategies: mixed ventilation (MV), displacement ventilation (DV), and local exhaust (Exhaust). Results demonstrated that the RELV system, optimized at a momentum ratio of 0.2, achieved a remarkable 72.9% aerosol removal efficiency within 120 s, significantly outperforming the 16.1% removal efficiency of the MV system under Scenario I, where the patient was located at the elevator’s center. Furthermore, the viral aerosol concentration in the breathing zone was reduced from 2.03×10⁻² mg/cm³ in the MV system to 1.02×10⁻³ mg/cm³ in the RELV system. The RELV system features simple design and compatibility with existing ventilation systems, offering an effective solution to improve air quality in elevators and other enclosed environments. Additionally, this study provides a velocity decay curve for low-velocity jets in the RELV system. This curve offers valuable insights for designing ventilation systems in similar settings.</p>