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<p>Explaining and predicting phenotypic differences remains a central challenge in microbiology. Metabolomics and population-scale proteomics bridge the gap between genotype, environment, and phenotypes by capturing the functional states from which they emerge. Together, they identify which genetic variants matter for fitness and how they become phenotypically relevant, uncover regulatory networks and metabolic constraints - thus advancing our understanding of microbial adaptation.</p>

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Vom Genotyp zum Phänotyp: mikrobielle Anpassung molekular entschlüsseln

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年5月16日

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  • Johannes Hartl

摘要

Explaining and predicting phenotypic differences remains a central challenge in microbiology. Metabolomics and population-scale proteomics bridge the gap between genotype, environment, and phenotypes by capturing the functional states from which they emerge. Together, they identify which genetic variants matter for fitness and how they become phenotypically relevant, uncover regulatory networks and metabolic constraints - thus advancing our understanding of microbial adaptation.