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<p>Viral inhibition requires innovative strategies. Supramolecular 2D structures inhibit viral entry through charge-based receptor mimicry. dPG-MUS and cholesteryl-oligo-glycerol-based surfactants form ordered structures with controlled multivalency that bind viral proteins. Their 2D architecture enables flexible encapsulation and physical shielding. Challenges include selectivity and scalability. These materials offer potential for broad-spectrum antiviral therapies targeting conserved entry mechanisms.</p>

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Supramolekulare 2D-Materialien zur Virushemmung

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年3月1日

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  • Ranen Etouki,
  • Jasmin Er,
  • Yangping Long,
  • Ehsan Mohammadifar,
  • Rainer Haag

摘要

Viral inhibition requires innovative strategies. Supramolecular 2D structures inhibit viral entry through charge-based receptor mimicry. dPG-MUS and cholesteryl-oligo-glycerol-based surfactants form ordered structures with controlled multivalency that bind viral proteins. Their 2D architecture enables flexible encapsulation and physical shielding. Challenges include selectivity and scalability. These materials offer potential for broad-spectrum antiviral therapies targeting conserved entry mechanisms.