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<p>Biological membranes display remarkable compositional diversity with functional consequences. In viral infections, lipids play active roles beyond forming a structural barrier: they modulate fusion protein binding, and tune membrane mechanics to prime them for efficient fusion, while viruses hijack host lipid metabolism to support replication. This highlights how membrane remodeling is exploited throughout the viral life cycle and points to potential avenues for antiviral intervention.</p>

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Lipide und Membranmechanik als aktive Regulatoren der Virusreplikation

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年3月1日

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  • Katharina C. Scherer,
  • Jochen S. Hub

摘要

Biological membranes display remarkable compositional diversity with functional consequences. In viral infections, lipids play active roles beyond forming a structural barrier: they modulate fusion protein binding, and tune membrane mechanics to prime them for efficient fusion, while viruses hijack host lipid metabolism to support replication. This highlights how membrane remodeling is exploited throughout the viral life cycle and points to potential avenues for antiviral intervention.