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<p>Fetal bovine serum (FBS) is still the gold standard growth factor supplement in mammalian cell culture, despite ethical, economic, and environmental concerns. Chemically synthesized and bio-derived products were identified as possible alternatives, however, with notable limitations like missing universal applicability among cell lines. Here, we present an animal-free, algae-based solution, in which native protein from <i>Galdieria sulphuraria</i> leads to proliferation of different mammalian cell lines.</p>

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Proteine aus Mikroalgen als Kälberserumersatz

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年2月25日

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  • Felicitas Berger,
  • Imke Lang

摘要

Fetal bovine serum (FBS) is still the gold standard growth factor supplement in mammalian cell culture, despite ethical, economic, and environmental concerns. Chemically synthesized and bio-derived products were identified as possible alternatives, however, with notable limitations like missing universal applicability among cell lines. Here, we present an animal-free, algae-based solution, in which native protein from Galdieria sulphuraria leads to proliferation of different mammalian cell lines.