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<p>Given its crucial contribution to organismal development and adaptation, gene expression is subject to stringent regulation. With light as an inducer, reversible, noninvasive, spatiotemporally precise, and automatable expression control is reached. We advance circuits that target transcription or translation; respond to blue, red, or infra-red light; and afford pronounced regulatory responses. Alone or combined, these setups unlock innovative applications in fundamental and applied research.</p>

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Lichtschalter zur Kontrolle bakterieller Transkription und Translation

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年3月25日

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  • Marius Blackholm,
  • Stefanie S. M. Meier,
  • Andreas Möglich

摘要

Given its crucial contribution to organismal development and adaptation, gene expression is subject to stringent regulation. With light as an inducer, reversible, noninvasive, spatiotemporally precise, and automatable expression control is reached. We advance circuits that target transcription or translation; respond to blue, red, or infra-red light; and afford pronounced regulatory responses. Alone or combined, these setups unlock innovative applications in fundamental and applied research.