Scholarlink

<p>Dynamic changes of the epigenome at specific gene loci, including alterations of chemical modifications on the DNA or histone proteins, are critical in development and disease. Bimolecular Anchor Detector (BiAD) sensors can be used to visualize these modifications in living cells with locus resolution. Recently, we improved the BiAD technology by enhancing the sensor sensitivity and expanded the range of detectable modifications, enabling a broad application of the BiAD sensors in various contexts.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Sensoren zur lokusspezifischen Visualisierung epigenetischer Modifikationen

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年3月25日

查看全文
  • Anja Regina Köhler,
  • Albert Jeltsch

摘要

Dynamic changes of the epigenome at specific gene loci, including alterations of chemical modifications on the DNA or histone proteins, are critical in development and disease. Bimolecular Anchor Detector (BiAD) sensors can be used to visualize these modifications in living cells with locus resolution. Recently, we improved the BiAD technology by enhancing the sensor sensitivity and expanded the range of detectable modifications, enabling a broad application of the BiAD sensors in various contexts.