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<p>The RNA species of microRNAs represents an important component of post-transcriptional gene regulation. Herpes viruses, including the Epstein-Barr virus, encode their own microRNA genes, which play a relevant role in crucial cellular processes, including immune evasion, but also in the malignant transformation of host cells. Modern transcriptome analyses, including RNA sequencing, contribute significantly to the identification of these direct and indirect molecular regulatory relationships.</p>

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RNA-Sequenzierung zur Analyse Epstein-Barr-Virus-codierter microRNAs

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年2月21日

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  • Tim Hohmann,
  • Simon Jasinski-Bergner

摘要

The RNA species of microRNAs represents an important component of post-transcriptional gene regulation. Herpes viruses, including the Epstein-Barr virus, encode their own microRNA genes, which play a relevant role in crucial cellular processes, including immune evasion, but also in the malignant transformation of host cells. Modern transcriptome analyses, including RNA sequencing, contribute significantly to the identification of these direct and indirect molecular regulatory relationships.