Naturstoffe aus der Vergangenheit
摘要
Low molecular weight compounds biosynthesized by microorganisms, commonly known as natural products, are indispensable in modern medicine. They serve as the basis for many antibiotics, immunomodulators, and anti cancer agents. The new research field of paleobiotechnology allows access to natural products of the past. Based on ancient DNA from dental calculus, it was possible to generate bacterial natural products dating back over 100,000 years.