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Struktureinblicke in die kotranslationale Qualitätskontrolle in Bakterien

  • Sebastian Filbeck,
  • Stefan Pfeffer

摘要

Translational quality control pathways counteract aberrant translation processes, such as ribosome stalling, and are key steps in maintaining a functional proteome. Recent cryo-electron microscopy and biochemical data provided valuable structural and mechanistic insights into hallmark steps of bacterial translational quality control, explaining how ribosome stalling is sensed and resolved.