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Neue Perspektiven der Aromaforschung: pilzliche O(S)-Methyltransferasen

  • Fabio F. Brescia,
  • Holger Zorn,
  • Martin Rühl

摘要

The demand for natural flavourings has driven a focus on enzymatic aroma production. Combining transcriptomics and aroma data unveiled a novel O-methyltransferase in Pleurotus sapidus, responsible for p-anisaldehyde formation. This enzyme catalysed the transmethylation of various aromatic compounds and a thiol nucleophile, classifying it as an O(S)-methyltransferase. The crystal structure was resolved at 2.0 Å, marking a significant milestone. These findings promise advances in natural flavour production.