Kleb‘s zusammen & zerleg‘s: Detergensproteine in der zelleigenen Immunität

The spread of antibiotic resistances among bacteria led to an increase in multidrug resistant pathogens. New therapies are urgently needed to tackle the current global antibiotic crisis. One strategy is to boost the ancient antimicrobial defense conserved in all vertebrates: the innate immune system. To develop such therapies, a fundamental understanding of host-pathogen interactions is crucial. We study how detergent-like host factors combat bacterial pathogens in cell-autonomous immunity.