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Tröpfchenmikrofluidik für das Enzymscreening

  • Martina Graf,
  • Ashkan Samimi,
  • Miriam A. Rosenbaum,
  • Sundar Hengoju

摘要

Directed evolution is a powerful tool for optimization of industrially relevant enzymes. But the vast sequence spaces of mutant libraries bring traditional screening methods to their limits. Droplet microfluidics, however, has a significantly higher throughput, with the capability to screen over million enzyme variants within few hours.