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<p>Atrial fibrillation (AF) is a common arrhythmia with significant morbidity and mortality, making it essential to conduct in-depth research on its mechanisms and treatments. Animal models are important tools in AF research because they can replicate the key pathophysiological features observed in human AF. This review summarizes various small animal models of AF, focusing on the construction methods of different models, the induction techniques for AF, and the corresponding induction rates, which provide important support for studying the mechanisms of AF and evaluating pharmacological efficacy.</p> Graphical Abstract <p></p>

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Small Animal Models for Translational Research in Atrial Fibrillation

  • 期刊论文

  • 发表日期：

    2026年7月20日

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  • Yunmeng Wang,
  • Jiaqi Wang,
  • Yawei Liu,
  • Jingchao Lu

摘要

Atrial fibrillation (AF) is a common arrhythmia with significant morbidity and mortality, making it essential to conduct in-depth research on its mechanisms and treatments. Animal models are important tools in AF research because they can replicate the key pathophysiological features observed in human AF. This review summarizes various small animal models of AF, focusing on the construction methods of different models, the induction techniques for AF, and the corresponding induction rates, which provide important support for studying the mechanisms of AF and evaluating pharmacological efficacy.

Graphical Abstract