Case Report - Low Grade Appendiceal Mucinous Neoplasia and Neuroendocrine Appendiceal Tumour: A Rare Coexistence
摘要
Appendiceal tumours are rare, accounting for 0.5 to 1% of gastrointestinal neoplasms, and collision tumours involving low-grade appendiceal mucinous neoplasia (LAMN) and neuroendocrine tumours (NET) are even rarer, with only a few cases reported. We present the case of a 43-year-old male who presented with right iliac fossa pain. Imaging suggested an appendiceal mucocele with features suspicious for neoplasm, and a right hemicolectomy was performed. Histopathology revealed two distinct tumours: LAMN in the proximal appendix and NET in the distal 1 cm. Both tumours were confined to the muscularis propria, margins were free, and six lymph nodes were tumour-free. Collision tumours of this kind are challenging to diagnose preoperatively as imaging often misses the NET component, which is typically discovered only on histological examination. Surgical management should be tailored based on tumour size, invasion, and metastasis risk. Long-term follow-up is essential. This case highlights the need for increased awareness of such rare entities.