Scholarlink

<p>Benign fibrous histiocytoma (BFH) is a common cutaneous soft tissue tumor but is rarely encountered in deep locations such as the anterior abdominal wall. Deep-seated BFH poses a diagnostic challenge as it can clinically mimic more aggressive spindle cell tumors, particularly desmoid-type fibromatosis. We report a rare case of a 47-year-old male presenting with a recurrent supra-umbilical mass, previously excised twice over a 15-year period and diagnosed as desmoid fibromatosis. Physical examination revealed a firm subcutaneous mass. Ultrasonography confirmed a soft tissue lesion distinct from the underlying rectus muscle, and Fine Needle Aspiration Cytology (FNAC) reported a benign spindle cell lesion. The patient underwent wide local excision. Histopathology demonstrated a storiform spindle-cell lesion with scattered giant cells. Immunohistochemistry showed negativity for nuclear β-catenin and focal positivity for CD34, confirming the diagnosis of deep benign fibrous histiocytoma. This case highlights the importance of differentiating BFH from desmoid fibromatosis using histopathology and immunohistochemistry, as the prognosis and management differ significantly.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Recurrent Benign Fibrous Histiocytoma of the Anterior Abdominal Wall Masquerading as Desmoid Fibromatosis

  • 期刊论文

  • 发表日期：

    2026年3月20日

查看全文
  • Harikishan Reddy Balappagari,
  • Peter Manoharan Chellappa,
  • Dharmendra M. Yadav,
  • Jeenu Elizabeth Cherian,
  • Kabilan S

摘要

Benign fibrous histiocytoma (BFH) is a common cutaneous soft tissue tumor but is rarely encountered in deep locations such as the anterior abdominal wall. Deep-seated BFH poses a diagnostic challenge as it can clinically mimic more aggressive spindle cell tumors, particularly desmoid-type fibromatosis. We report a rare case of a 47-year-old male presenting with a recurrent supra-umbilical mass, previously excised twice over a 15-year period and diagnosed as desmoid fibromatosis. Physical examination revealed a firm subcutaneous mass. Ultrasonography confirmed a soft tissue lesion distinct from the underlying rectus muscle, and Fine Needle Aspiration Cytology (FNAC) reported a benign spindle cell lesion. The patient underwent wide local excision. Histopathology demonstrated a storiform spindle-cell lesion with scattered giant cells. Immunohistochemistry showed negativity for nuclear β-catenin and focal positivity for CD34, confirming the diagnosis of deep benign fibrous histiocytoma. This case highlights the importance of differentiating BFH from desmoid fibromatosis using histopathology and immunohistochemistry, as the prognosis and management differ significantly.