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<p>Colorectal malignancy is the third most common malignancy, and the association with gallbladder malignancy is extremely rare. The simultaneous presentation of gallbladder and colonic malignancy has been reported in only 9 cases in the literature to date. The coexistence of intestinal tuberculosis with para-aortic lymphadenopathy often poses diagnostic challenges in assessing the nodal status. Here, we report a case of 62-year-old lady who presented with abdominal pain and melena, with no previous history of tuberculosis and an unremarkable physical examination. Upon evaluation, she was found to have a polypoid lesion in the gallbladder, a growth in the sigmoid colon, and para-aortic lymphadenopathy. The patient underwent laparoscopic aorto-caval node frozen biopsy, which suggested necrotising granuloma. Subsequently, she underwent laparoscopic curative radical cholecystectomy and sigmoid colectomy. The final histopathology examination revealed gallbladder adenocarcinoma and sigmoid colon adenocarcinoma with para-aortic nodal tuberculosis.</p>

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Unveiling the Mystery: Para-aortic Tuberculous Lymphadenopathy in Synchronous Gallbladder and Colon Carcinoma

  • 期刊论文

  • 发表日期：

    2026年3月24日

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  • Sakthivel Chinnakkulam Kandhasamy,
  • Shymole Viswambharan,
  • Varghese Yeldho,
  • Shabeerali T.U.

摘要

Colorectal malignancy is the third most common malignancy, and the association with gallbladder malignancy is extremely rare. The simultaneous presentation of gallbladder and colonic malignancy has been reported in only 9 cases in the literature to date. The coexistence of intestinal tuberculosis with para-aortic lymphadenopathy often poses diagnostic challenges in assessing the nodal status. Here, we report a case of 62-year-old lady who presented with abdominal pain and melena, with no previous history of tuberculosis and an unremarkable physical examination. Upon evaluation, she was found to have a polypoid lesion in the gallbladder, a growth in the sigmoid colon, and para-aortic lymphadenopathy. The patient underwent laparoscopic aorto-caval node frozen biopsy, which suggested necrotising granuloma. Subsequently, she underwent laparoscopic curative radical cholecystectomy and sigmoid colectomy. The final histopathology examination revealed gallbladder adenocarcinoma and sigmoid colon adenocarcinoma with para-aortic nodal tuberculosis.