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<p>Cardiac-specific Troponin-I (TnI) is a well-established marker for myocardial injury,commonly used to predict early cardiac mortality. Postoperative TnI elevation isassociated with myocardial injury, but its prognostic significance in non-cardiacgastrointestinal surgery remains unclear. This study evaluated whether postoperativeTnI predicts 30-day mortality, morbidity, and duration of ICU and hospital stay.&#xa0;Perioperative data were prospectively collected and retrospectively analyzed.Postoperative TnI was measured 12–24 hours after surgery and categorized into ≤19ng/L or &gt;19 ng/L. Primary outcome was 30-day mortality; secondary outcomesincluded morbidity and length of ICU/hospital stay.&#xa0;Of the 235 patients included, 119 had Trop-I ≤19 ng/L, and 116 had Trop-I &gt;19 ng/L.Both groups were comparable in terms of demographic and clinical parameters.Elevated TnI was associated with higher 30-day mortality (19.05% vs 0.84%, <i>p</i> =0.003), morbidity (66.67% vs 3.36%, <i>p</i> &lt; 0.001), and longer ICU/hospital stays.&#xa0;Our study demonstrates that elevated postoperative Trop-I levels are stronglyassociated with increased morbidity, mortality, and prolonged hospital and ICU staysfollowing gastrointestinal surgeries. Further large-scale studies are needed to validatethese findings, and routine postoperative measurement is recommended.</p>

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Prognostic Value of Postoperative Troponin-I in Non-Cardiac Gastrointestinal Surgeries

  • 期刊论文

  • 发表日期：

    2026年3月14日

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  • Bhatt Keyur,
  • Mangukiya Dhaval,
  • Kachhadiya Daxa

摘要

Cardiac-specific Troponin-I (TnI) is a well-established marker for myocardial injury,commonly used to predict early cardiac mortality. Postoperative TnI elevation isassociated with myocardial injury, but its prognostic significance in non-cardiacgastrointestinal surgery remains unclear. This study evaluated whether postoperativeTnI predicts 30-day mortality, morbidity, and duration of ICU and hospital stay. Perioperative data were prospectively collected and retrospectively analyzed.Postoperative TnI was measured 12–24 hours after surgery and categorized into ≤19ng/L or >19 ng/L. Primary outcome was 30-day mortality; secondary outcomesincluded morbidity and length of ICU/hospital stay. Of the 235 patients included, 119 had Trop-I ≤19 ng/L, and 116 had Trop-I >19 ng/L.Both groups were comparable in terms of demographic and clinical parameters.Elevated TnI was associated with higher 30-day mortality (19.05% vs 0.84%, p =0.003), morbidity (66.67% vs 3.36%, p < 0.001), and longer ICU/hospital stays. Our study demonstrates that elevated postoperative Trop-I levels are stronglyassociated with increased morbidity, mortality, and prolonged hospital and ICU staysfollowing gastrointestinal surgeries. Further large-scale studies are needed to validatethese findings, and routine postoperative measurement is recommended.