Renal transplantation is used as a treatment for patients with end-stage renal failure. Renal transplant patients (RTPs) must take immunosuppressive drugs for the rest of their lives to ensure graft survival. Consequently, the most common malignancies causing morbidity and mortality in RTPs are skin cancers (Oh et al. Singapore Med J 59:519-23, 2018). Non-melanoma skin cancers (NMSC), particularly SCC (Squamous cell carcinoma) and BCC (Basal cell carcinoma), are the most common skin cancers observed after transplantation. Compared to the general population, the incidence of SCC and BCC in RTPs is 10–16 and 65–250 times greater, respectively (Perez et al. Int J Dermatol 4:370-378, 2017). Tumors may exhibit more aggressive, fast-growing, and destructive behavior in RTPs than in the general population, leading to higher morbidity and mortality (Jenni et al. Curr Probl Dermatol 46: 49-57, 2015). Several studies showed that RTPs present with SCC, BCC, or both at first presentation (Wisgerhof et al. 89:1231-8, 2010). The literature indicates that the initial tumor type is often indicative of subsequent tumor types (Wisgerhof et al. 89:1231-8, 2010). Nevertheless, it is uncommon for two distinct neoplasms to coexist at the time of initial presentation. Presently, we described a rare RTP who presented with multiple SCCs and BCCs growing rapidly on his face at the same time.
