Scholarlink

<p>Pacinian corpuscles are specialized mechanoreceptors responsible for sensing deep pressure and vibration. They are typically found in glabrous skin and certain visceral sites. Their occurrence within lymph nodes is exceedingly uncommon. We report the case of a 57-year-old man with well-differentiated squamous cell carcinoma of the penis who underwent bilateral inguinal lymphadenectomy. Histologic examination of one lymph node revealed a well-formed, lamellated Pacinian corpuscle within the nodal parenchyma, an exceptional incidental finding representing one of very few documented cases worldwide. Immunohistochemistry performed on available tissue highlighted the neuroectodermal nature of the corpuscle. Although of uncertain biological significance, recognition of Pacinian corpuscles within lymph nodes is important to prevent diagnostic confusion with pathologic inclusions or tumor deposits in oncologic specimens.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Inguinal Lymph Nodal Pacinian Corpuscle in a Known Case of Squamous Cell Carcinoma Penis: A Case Report

  • 期刊论文

  • 发表日期：

    2026年2月16日

查看全文
  • Bhoomika Kaushik,
  • Rakesh Kumar Gupta,
  • Amit R. Sharma

摘要

Pacinian corpuscles are specialized mechanoreceptors responsible for sensing deep pressure and vibration. They are typically found in glabrous skin and certain visceral sites. Their occurrence within lymph nodes is exceedingly uncommon. We report the case of a 57-year-old man with well-differentiated squamous cell carcinoma of the penis who underwent bilateral inguinal lymphadenectomy. Histologic examination of one lymph node revealed a well-formed, lamellated Pacinian corpuscle within the nodal parenchyma, an exceptional incidental finding representing one of very few documented cases worldwide. Immunohistochemistry performed on available tissue highlighted the neuroectodermal nature of the corpuscle. Although of uncertain biological significance, recognition of Pacinian corpuscles within lymph nodes is important to prevent diagnostic confusion with pathologic inclusions or tumor deposits in oncologic specimens.