Scholarlink

<p>Hepatocellular carcinoma (HCC) with tumor thrombus involving major vessels often indicates an unresectable advanced stage and poor prognosis. Targeting-intratumoral-lactic-acidosis transarterial chemoembolization (TILA-TACE) combined with three-dimensional conformal radiation therapy (3D-CRT) may downstage HCC and improve resectability. We report a 60-year-old man presenting with a one-month history of constipation. Magnetic resonance imaging revealed a hepatic mass with tumor thrombus of the right hepatic vein extended to the inferior vena cava proximal to the right atrium. A clinical diagnosis of stage IIIa HCC was established. The patient underwent TILA-TACE, 3D-CRT, and a second TILA-TACE in turn, with a two-week interval respectively. As a result, the tumor thrombus reduced within a resectable range, subsequently, the right hemihepatectomy was successfully performed. After surgery, the patient recovered uneventfully. In conclusion, TILA-TACE combined with 3D-CRT could take effects on the unresectable HCC mentioned above, likely converting an unresectable or a potential resectable HCC into a resectable one.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Conversional Effects of TILA-TACE Combined with 3D-CRT on An Unresectable HCC with Type IIIb Tumor Thrombus in the Right Hepatic Vein

  • 期刊论文

  • 发表日期：

    2026年2月4日

查看全文
  • Jun-Hui Wu,
  • Zhong Jia,
  • Qi-Jun Yang,
  • He-Shan Zhou

摘要

Hepatocellular carcinoma (HCC) with tumor thrombus involving major vessels often indicates an unresectable advanced stage and poor prognosis. Targeting-intratumoral-lactic-acidosis transarterial chemoembolization (TILA-TACE) combined with three-dimensional conformal radiation therapy (3D-CRT) may downstage HCC and improve resectability. We report a 60-year-old man presenting with a one-month history of constipation. Magnetic resonance imaging revealed a hepatic mass with tumor thrombus of the right hepatic vein extended to the inferior vena cava proximal to the right atrium. A clinical diagnosis of stage IIIa HCC was established. The patient underwent TILA-TACE, 3D-CRT, and a second TILA-TACE in turn, with a two-week interval respectively. As a result, the tumor thrombus reduced within a resectable range, subsequently, the right hemihepatectomy was successfully performed. After surgery, the patient recovered uneventfully. In conclusion, TILA-TACE combined with 3D-CRT could take effects on the unresectable HCC mentioned above, likely converting an unresectable or a potential resectable HCC into a resectable one.