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<p>Pelvic organ prolapse (POP) is a prevalent condition that significantly impacts women’s quality of life. Sacrocolpopexy is the gold standard surgical treatment for apical prolapse. This study hypothesized that vaginal natural orifice transluminal endoscopic surgery sacrocolpopexy (V-NOTES-SCP) could provide comparable or superior outcomes to laparoscopic sacrocolpopexy (LS-SCP). This case series included 45 patients with stage III or IV apical prolapse, preserved uteri, and no prior hysterectomy. Patients were divided into two groups: LS-SCP (<i>n</i> = 30) and V-NOTES-SCP (<i>n</i> = 15). Operative time, blood loss, hospitalization duration, and pelvic organ prolapse quantification (POP-Q) scores were analyzed. Statistical significance was set at <i>p</i> &lt; 0.05. Operative time was significantly shorter in the V-NOTES-SCP group (70.9&#xa0;min) compared to the LS-SCP group (85.9&#xa0;min, <i>p</i> &lt; 0.05). Both groups exhibited significant postoperative improvements in POP-Q scores. The V-NOTES-SCP group achieved superior cosmetic outcomes, while hospitalization durations were similar in both groups. No major complications were reported. V-NOTES-SCP demonstrated shorter operative times and superior cosmetic outcomes compared to LS-SCP, highlighting its potential as a safe and effective minimally invasive alternative for apical prolapse treatment. Further studies with larger cohorts and longer follow-up are required to validate these findings.</p>

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A Comparative Feasibility Study of V-NOTES Sacrocolpopexy and Laparoscopic Sacrocolpopexy

  • 期刊论文

  • 发表日期：

    2025年2月14日

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  • Eralp Bulutlar,
  • Gizem Berfin Uluutku Bulutlar,
  • Ayşe Betül Albayrak Denizli,
  • Çetin Kılıççı

摘要

Pelvic organ prolapse (POP) is a prevalent condition that significantly impacts women’s quality of life. Sacrocolpopexy is the gold standard surgical treatment for apical prolapse. This study hypothesized that vaginal natural orifice transluminal endoscopic surgery sacrocolpopexy (V-NOTES-SCP) could provide comparable or superior outcomes to laparoscopic sacrocolpopexy (LS-SCP). This case series included 45 patients with stage III or IV apical prolapse, preserved uteri, and no prior hysterectomy. Patients were divided into two groups: LS-SCP (n = 30) and V-NOTES-SCP (n = 15). Operative time, blood loss, hospitalization duration, and pelvic organ prolapse quantification (POP-Q) scores were analyzed. Statistical significance was set at p < 0.05. Operative time was significantly shorter in the V-NOTES-SCP group (70.9 min) compared to the LS-SCP group (85.9 min, p < 0.05). Both groups exhibited significant postoperative improvements in POP-Q scores. The V-NOTES-SCP group achieved superior cosmetic outcomes, while hospitalization durations were similar in both groups. No major complications were reported. V-NOTES-SCP demonstrated shorter operative times and superior cosmetic outcomes compared to LS-SCP, highlighting its potential as a safe and effective minimally invasive alternative for apical prolapse treatment. Further studies with larger cohorts and longer follow-up are required to validate these findings.