Immediate Breast Reconstruction After Nipple-Sparing Mastectomy with Prepectoral Implant Placement Supported by a Partial Coverage Technique Employing Late Absorbable Synthetic Mesh

This study aimed to present the outcomes our experience with nipple-sparing mastectomy and single-stage with prepectoral implant placement and employing a fully synthetic late absorbable mesh. The study retrospectively examined 62 patients and 78 breasts of nipple-sparing mastectomy and single-stage direct-to-implant breast reconstruction with prepectoral implant placement supported by a partial coverage technique employing late absorbable synthetic mesh coverage of the implant. In a cohort of 62 patients undergoing nipple-sparing mastectomy with single-stage reconstruction, the study evaluated clinical characteristics, surgical outcomes, and long-term follow-up. Perioperative assessments indicated excellent flap viabilities. Pathology results revealed acceptable oncological safety. Adverse events included seroma (4.84%), hematoma (3.23%), wound infection (14.52%), and mastectomy flap necrosis (12.90%). Patients expressed a high satisfaction rate (80.64%) with excellent cosmetic outcomes, and implant-related issues were minimal during follow-up. Overall, the study provided comprehensive insights into the efficacy and safety of the nipple-sparing mastectomy—partial coverage technique procedure. The evidence from these studies supports the consideration of single-stage nipple-sparing mastectomy—reconstruction with prepectoral implant placement for patients with early-stage breast cancer who meet the criteria for nipple-sparing mastectomy.