The Therapeutic Effect of Bleomycin Sclerotherapy in Vascular Malformations

Sclerotherapy is a frequently employed technique for treating vascular malformations. Bleomycin is a sclerosant that has demonstrated efficacy and safety in this particular approach. The aim of this study is to investigate the efficacy of bleomycin sclerotherapy in treating vascular malformations. In this study, we reviewed all the studies that fit the subject of our research with the keywords bleomycin and vascular malformations in the title and abstract in PubMed from 2004 to June 12, 2023, to prevent selection bias. Most studies support bleomycin’s efficacy and safety as a sclerosant agent. A few studies have observed its distressing side effect, pulmonary fibrosis. The variety of vascular malformations and the lack of a unique classification system appear to hinder the accurate measurement of this method’s efficacy.