Scholarlink

<p>Targeted drug delivery within advanced systems represents one of the most promising strategies for achieving superior therapeutic outcomes. Among the emerging materials investigated for this purpose, nanocomposites have demonstrated exceptional potential in the design of highly selective and efficient delivery platforms. In particular, titanium dioxide (TiO₂) nanoparticles (NPs) have attracted considerable scientific interest due to their unique physicochemical characteristics, stability, and biocompatibility, which make them highly suitable for diverse biomedical applications. However, comprehensive biological characterization remains essential to fully harness their capabilities for future translational research. In the present study, titanium NPs were synthesized using the angle deposition technique, a controlled fabrication method that enables precise NPs formation. The NPs were deposited onto a glass substrate and subsequently extracted through ultrasonication to obtain a stable NP suspension for experimental analysis. The results obtained from the characterization and biological assessment of the synthesized NPs were highly encouraging. In vitro investigations conducted using erythrocytes and platelet-rich plasma demonstrated promising interactions relevant to targeted drug delivery mechanisms. Notably, the TiO₂ exhibited favorable compatibility with blood components and contributed to measurable enhancement in platelet morphology and size through natural sensing interactions. To ensure high analytical precision, advanced image processing techniques were employed for accurate measurement and morphological evaluation of platelets and red blood cells (RBCs). The findings of this study strongly suggest that TiO₂ NPs possess significant potential as targeted drug delivery agents. Their ability to interact effectively with biological systems indicates promising applications in the treatment of critical diseases such as cancer, inflammatory disorders, osteoporosis, and thrombosis. These results provide a compelling foundation for further investigation into TiO₂-based nanomaterials as next-generation therapeutic delivery platforms.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Experimental Investigation of Titania Nanocarriers for Biomedical Applications

  • 期刊论文

  • 发表日期：

    2026年5月4日

查看全文
  • Shubhro Chakrabartty,
  • Sachin Kumar,
  • Md Iqbal Alam,
  • Hala Mostafa,
  • Bhawna Goyal

摘要

Targeted drug delivery within advanced systems represents one of the most promising strategies for achieving superior therapeutic outcomes. Among the emerging materials investigated for this purpose, nanocomposites have demonstrated exceptional potential in the design of highly selective and efficient delivery platforms. In particular, titanium dioxide (TiO₂) nanoparticles (NPs) have attracted considerable scientific interest due to their unique physicochemical characteristics, stability, and biocompatibility, which make them highly suitable for diverse biomedical applications. However, comprehensive biological characterization remains essential to fully harness their capabilities for future translational research. In the present study, titanium NPs were synthesized using the angle deposition technique, a controlled fabrication method that enables precise NPs formation. The NPs were deposited onto a glass substrate and subsequently extracted through ultrasonication to obtain a stable NP suspension for experimental analysis. The results obtained from the characterization and biological assessment of the synthesized NPs were highly encouraging. In vitro investigations conducted using erythrocytes and platelet-rich plasma demonstrated promising interactions relevant to targeted drug delivery mechanisms. Notably, the TiO₂ exhibited favorable compatibility with blood components and contributed to measurable enhancement in platelet morphology and size through natural sensing interactions. To ensure high analytical precision, advanced image processing techniques were employed for accurate measurement and morphological evaluation of platelets and red blood cells (RBCs). The findings of this study strongly suggest that TiO₂ NPs possess significant potential as targeted drug delivery agents. Their ability to interact effectively with biological systems indicates promising applications in the treatment of critical diseases such as cancer, inflammatory disorders, osteoporosis, and thrombosis. These results provide a compelling foundation for further investigation into TiO₂-based nanomaterials as next-generation therapeutic delivery platforms.