<p>This study provides foundational research for the domestic development of hydrogen refueling station components by conducting coupled fluid–structure interaction analysis and experiments to evaluate the structural safety of existing hydrogen refueling nozzles. Using fluid-induced pressure as boundary conditions, the analysis assessed equivalent stresses and deformations and derived safety factors based on the yield strength of materials. While the majority of components were found to be structurally safe, a poppet-like component exhibited maximum equivalent stress and structural instability. This was validated by a pressure cycling test conducted according to ISO 19880-3, which revealed damage consistent with the analysis results. Therefore, modifications to the internal flow path of the poppet-like component are necessary.</p>