Scholarlink

<p>As one of the most significant global health emergencies, COVID-19 has placed extraordinary demands on healthcare systems worldwide. In India, its widespread transmission has been influenced by the country’s diverse climatic conditions, geo-ecological complexity, and dense population. This, vector-borne diseases (VBDs)—including malaria, dengue, kala azar, Japanese encephalitis, and chikungunya—have long posed additional challenges to public health infrastructure. Intriguingly, prior exposure to these diseases may shape immune responses, potentially conferring cross-protection against multiple pathogens. A cross-sectional study aimed at assessing the role of VBDs in COVID-19 incidence and mortality revealed a multifaceted relationship. Prior dengue exposure was linked to an increased risk of SARS-CoV-2 infection and mortality, whereas kala azar, Japanese encephalitis, and chikungunya appeared to have protective influences. Notably, malaria had statistically significant protective effects against both SARS-CoV-2 infection and mortality (<i>p</i> &lt; 0.04). These findings suggest that immune mechanisms—such as cross-reactive antibodies or immune regulation—may alter susceptibility to COVID-19. Given the substantial protective effect of malaria, further investigation is warranted to clarify the underlying biological processes involved. Insights from this study could guide public health strategies, optimize resource allocation, and refine intervention measures in regions where both COVID-19 and VBDs remain major concerns.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Vector-borne diseases and their role in COVID-19 dynamics and death rates: focus on India

  • 期刊论文

  • 发表日期：

    2025年8月9日

查看全文
  • Satyananda Patel,
  • Maneesh Kumar,
  • Ganesh Chandra Sahoo,
  • Sushil Kumar Sahu

摘要

As one of the most significant global health emergencies, COVID-19 has placed extraordinary demands on healthcare systems worldwide. In India, its widespread transmission has been influenced by the country’s diverse climatic conditions, geo-ecological complexity, and dense population. This, vector-borne diseases (VBDs)—including malaria, dengue, kala azar, Japanese encephalitis, and chikungunya—have long posed additional challenges to public health infrastructure. Intriguingly, prior exposure to these diseases may shape immune responses, potentially conferring cross-protection against multiple pathogens. A cross-sectional study aimed at assessing the role of VBDs in COVID-19 incidence and mortality revealed a multifaceted relationship. Prior dengue exposure was linked to an increased risk of SARS-CoV-2 infection and mortality, whereas kala azar, Japanese encephalitis, and chikungunya appeared to have protective influences. Notably, malaria had statistically significant protective effects against both SARS-CoV-2 infection and mortality (p < 0.04). These findings suggest that immune mechanisms—such as cross-reactive antibodies or immune regulation—may alter susceptibility to COVID-19. Given the substantial protective effect of malaria, further investigation is warranted to clarify the underlying biological processes involved. Insights from this study could guide public health strategies, optimize resource allocation, and refine intervention measures in regions where both COVID-19 and VBDs remain major concerns.