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<p>Polymer science and nanotechnology play a vital role in recent years especially in the health and medical fields. The current approach represents a recent investigation for exploiting biopolymers blend of carboxymethyl starch and carboxymethyl chitosan for successive clustering of nitrogen-decorated carbon quantum dots (N-CQDs) with sequential entrapping of iodine (I<sub>2</sub>@N-CQDs). A comparable overview is studied between the ingrowth of N-CQDs under the effect of sodium hydroxide (I<sub>2</sub>@N-CQDs-S) versus formic acid (I<sub>2</sub>@N-CQDs-F). The obtained I<sub>2</sub>@N-CQDs were loaded within gauze matrix to prepare I<sub>2</sub>@N-CQDs@Gauze with anti-microbial and anti-inflammatory properties. The data reveal that nucleation of N-CQDs under basic conditions (N-CQDs-S, 7.2&#xa0;nm) is performed with smaller sized CQDs than that under acidic conditions (N-CQDs-F, 11.8&#xa0;nm). After iodine entrapping, size average increased to be 17.9 and 27.4&#xa0;nm for I<sub>2</sub>@N-CQDs-S and I<sub>2</sub>@N-CQDs-F, respectively. I<sub>2</sub>@N-CQDs-S@Gauze showed higher anti-inflammation than I<sub>2</sub>@N-CQDs-F@Gauze, while the estimated IC50 was 156.8 and 229.9&#xa0;µL, respectively. For anti-microbial performance, I<sub>2</sub>@N-CQDs-F@Gauze exhibited slightly higher results, and the microbial reduction was 78.2%, 76.1 &amp; 83.0% against <i>S</i>. <i>aureus</i>, <i>E. coli</i>, and<i> C. albicans</i>, respectively. Hence, the prepared I<sub>2</sub>@N-CQDs@Gauze could be promisingly applicable as bandage in wound healing for injuries treatment. </p>

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Biopolymers Blend for Microwave-Synthesized Carbon Dots and Iodine Entrapping for Potential Biomedical Bandages

  • 期刊论文

  • 发表日期：

    2025年6月13日

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  • Alaa M. Alqahtani,
  • Haifa Alharbi,
  • Sara A. Alqarni,
  • Gadeer R. S. Ashour,
  • Abeer A. Ageeli,
  • Hayfa H. Almutairi,
  • Khadra B. Alomari,
  • Nashwa M. El-Metwaly

摘要

Polymer science and nanotechnology play a vital role in recent years especially in the health and medical fields. The current approach represents a recent investigation for exploiting biopolymers blend of carboxymethyl starch and carboxymethyl chitosan for successive clustering of nitrogen-decorated carbon quantum dots (N-CQDs) with sequential entrapping of iodine (I2@N-CQDs). A comparable overview is studied between the ingrowth of N-CQDs under the effect of sodium hydroxide (I2@N-CQDs-S) versus formic acid (I2@N-CQDs-F). The obtained I2@N-CQDs were loaded within gauze matrix to prepare I2@N-CQDs@Gauze with anti-microbial and anti-inflammatory properties. The data reveal that nucleation of N-CQDs under basic conditions (N-CQDs-S, 7.2 nm) is performed with smaller sized CQDs than that under acidic conditions (N-CQDs-F, 11.8 nm). After iodine entrapping, size average increased to be 17.9 and 27.4 nm for I2@N-CQDs-S and I2@N-CQDs-F, respectively. I2@N-CQDs-S@Gauze showed higher anti-inflammation than I2@N-CQDs-F@Gauze, while the estimated IC50 was 156.8 and 229.9 µL, respectively. For anti-microbial performance, I2@N-CQDs-F@Gauze exhibited slightly higher results, and the microbial reduction was 78.2%, 76.1 & 83.0% against S. aureus, E. coli, and C. albicans, respectively. Hence, the prepared I2@N-CQDs@Gauze could be promisingly applicable as bandage in wound healing for injuries treatment.