<p>Pathogenic bacteria detection is critical in safeguarding human health and social security, such as disease diagnosis, environmental monitoring, food safety, and other fields. To overcome the disadvantages of traditional detection technologies, including complex operational procedures and long detection times, this study focuses on developing a high-sensitivity detection system based on giant magnetoresistance (GMR) magnetic biosensors. The integrated system was designed as an efficient detection instrument, including magnetic nanotags, GMR biosensors, a miniaturized hardware testing circuit, and a software testing system, which was employed for detecting different bacterial species. The application results of the principal prototype show that the system can make rapid and accurate detection for pathogenic bacteria in mobile laboratories and public health safety fields for a bio-safety fast response system, achieving the goal of rapid identification and early warning to the threatening pathogenic bacteria.</p>

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High-Sensitivity Giant Magnetoresistance Magnetic Biosensors and Pathogenic Bacteria Detection

  • Xun Sun,
  • Yun He,
  • Ying Cui,
  • Peihong Ma

摘要

Pathogenic bacteria detection is critical in safeguarding human health and social security, such as disease diagnosis, environmental monitoring, food safety, and other fields. To overcome the disadvantages of traditional detection technologies, including complex operational procedures and long detection times, this study focuses on developing a high-sensitivity detection system based on giant magnetoresistance (GMR) magnetic biosensors. The integrated system was designed as an efficient detection instrument, including magnetic nanotags, GMR biosensors, a miniaturized hardware testing circuit, and a software testing system, which was employed for detecting different bacterial species. The application results of the principal prototype show that the system can make rapid and accurate detection for pathogenic bacteria in mobile laboratories and public health safety fields for a bio-safety fast response system, achieving the goal of rapid identification and early warning to the threatening pathogenic bacteria.